. Author manuscript; available in PMC: 2024 Jul 1.

Published in final edited form as: J Am Geriatr Soc. 2023 Feb 28;71(7):2219–2228. doi: 10.1111/jgs.18305

TABLE 3.

Factors associated with supplement/complementary and alternative medication use in older women and men in the ASPirin in Reducing Events in the Elderly cohort.^a

	Women (n = 8477)		Men (n = 6507)
Variables	OR (95% CI)	P	OR (95% CI)	P

Age (per year)	0.98 (0.97–0.99)	<0.001	1.00 (0.99–1.01)	0.998
Education (ref ≤ 12 years education)	1.03 (0.93–1.14)	0.609	1.39 (1.26–1.54)	<0.001
Country (ref Aus)	2.04 (1.71–2.44)	<0.001	1.89 (1.55–2.31)	<0.001
Living situation (ref living alone)	0.83 (0.76–0.91)	<0.001	0.92 (0.82–1.03)	0.158
Polypharmacy	1.30(1.16–1.46)	<0.001	1.14 (1.01–1.29)	0.033
Diabetes	0.70 (0.60–0.81)	<0.001	0.97 (0.85–1.11)	0.656
Dyslipidemia	0.88 (0.75–1.02)	0.097	1.14 (1.01–1.27)	0.029
Frailty	1.10(1.02–1.18)	0.016	1.04 (0.96–1.13)	0.331
Development of MACE in-trial^b	0.60 (0.43–0.83)	0.002	0.78 (0.60–1.02)	0.072

Abbreviations: CI, confidence interval; OR, odds ratio.

Multivariate regression analysis stratified by sex. Values given as adjusted odds ratios (95% CI).

MACE: major adverse cardiovascular events including nonfatal myocardial infarction and fatal or nonfatal ischemic stroke.