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ANO1 is a druggable target for the targeted treatment of GI cancers. Inhibition effectiveness of CAI/BBR on the in vitro proliferation were measured with multiple A) human GC, B) EC, C) CRC cell lines, and D) mouse CRC cell line MC38. Inhibition effectiveness of CAI/BBR on the in vivo tumor growth were measure with E) an ANO1‐positive GC PDX, F) an ANO1‐negative GC PDX, and G) a GIST PDX with medium ANO1 expression. *p < 0.05. ns, not significant. Error bars, mean ± SEM.
