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. 2023 Aug 14;10:1229972. doi: 10.3389/fmed.2023.1229972

Table 3.

Validity and reliability of the Berlin questionnaire obtained in different published studies.

Studies Netzer (12) Polanía-Dussan (19) Bouloukaki (20) Lauritzen (21) Present study
Place and year Germany 1996 Colombia 2013 Greece 2013 Denmark 2018 Spain 2022
Type and number of patients studied General primary care n = 744 General n = 212 General primary care n = 189 Sleep clinic n = 206 General. primary care n = 266
Used sleep test PSG PSG PSG CRM HRM
Sex NA Men: 54.25% Woman: 45.75% Men: 61.9% Woman: 38.1% Men: 69.4% Woman: 30.6% Men: 54.12% Woman: 45.88%
AUC NA 0.785 0.59 NA 0.786
Sensitivity 86% 87% 76% (AHI ≥5 y <15) 84% (AH ≥15 y ≤30) 79% (AHI >30) 84% 76.77%
Specificity 77% 70% 40% (AHI ≥5 y <15) 61% (AHI ≥15 y ≤30) 39% (AHI >30) 17% 74.49%
VPP 89% 98% 80–94% 69% 75.25%
VPN NA 21% NA 33% 76.04%
Cronbach’s alpha coefficient 0.86–0.92 NA NA NA 0.730
Kappa index 0.68–0.98 0.7257 NA NA 0.739

PSG, polysomnography; CRM, cardiac respiratory monitoring; HRP, home respiratory polygraphy; AUC, area under the curve; AHI, apnea-hypopnea index; PPV, positive predictive value; NPV, negative predictive value; NA, not available.