Table 1.
Characteristics of patients with diagnosed AF in the intervention and control arms
| Intervention | Control | |
|---|---|---|
| Total no. | 2250 | 2343 |
| Age (y) | 78.3 ± 7.6 | 78.4 ± 7.7 |
| Age >75 y | 1411 (62.7) | 1486 (63.4) |
| Female | 927 (41.2) | 1008 (43.0) |
| Race/ethnicity∗ | ||
| White | 2003 (89.0) | 2070 (88.3) |
| Black | 52 (2.3) | 50 (2.1) |
| Hispanic | 34 (1.5) | 39 (1.7) |
| Other | 121 (5.4) | 147 (6.3) |
| Height (cm)∗ | 168.6 ± 11.5 | 167.8 ± 11.3 |
| Weight (kg)∗ | 81.6 ± 19.7 | 81.1 ± 19.8 |
| Body mass index (kg/m2)∗ | 28.5 ± 5.8 | 28.6 ± 6.0 |
| Systolic blood pressure (mm Hg)∗ | 129.2 ± 16.8 | 128.4 ± 17.0 |
| Diastolic blood pressure (mm Hg)∗ | 73.0 ± 9.3 | 72.1 ± 9.4 |
| Oral anticoagulant | 1511 (67.2) | 1601 (68.3) |
| Antiplatelet therapy | 196 (8.7) | 221 (9.4) |
| Rate control therapy, any | 2030 (90.2) | 2126 (90.7) |
| Antiarrhythmic therapy, any | 501 (22.3) | 537 (22.9) |
| Left atrial appendage occlusion | 20 (0.9) | 18 (0.8) |
| Ablation | 106 (4.7) | 94 (4.0) |
| Cardioversion | 239 (10.6) | 256 (10.9) |
| Antihypertensive | 2007 (89.2) | 2085 (89.0) |
| Hypertension | 2074 (92.2) | 2169 (92.6) |
| Myocardial infarction | 483 (21.5) | 530 (22.6) |
| Coronary artery disease | 1210 (53.8) | 1263 (53.9) |
| Diabetes mellitus | 717 (31.9) | 779 (33.2) |
| Heart failure | 1083 (48.1) | 1188 (50.7) |
| Previous stroke | 487 (21.6) | 517 (22.1) |
| Vascular disease | 1089 (48.4) | 1116 (47.6) |
| Anemia | 999 (44.4) | 1059 (45.2) |
| Previous hemorrhage | 1005 (44.7) | 1142 (48.7) |
| Renal disease | 703 (31.2) | 792 (33.8) |
| Liver disease | 410 (18.2) | 456 (19.5) |
| Current smoker | 71 (3.2) | 86 (3.7) |
| CHA2DS2VASc score | 4.7 ± 1.7 | 4.7 ± 1.7 |
| Low risk† | 55 (2.4) | 63 (2.7) |
| Moderate risk† | 736 (32.7) | 695 (29.7) |
| High risk† | 1459 (64.8) | 1585 (67.6) |
| ATRIA bleed score | 4.9 ± 2.8 | 5.1 ± 2.9 |
Values are given as mean ± SD or n (%).
AF = atrial fibrillation; ATRIA = Anticoagulation and Risk Factors in Atrial Fibrillation.
∗
Variables with missing data: race : n = 77 (1.7%); height: n = 6 (0.13%); weight: n = 7 (0.15%); body mass index: n = 14 (0.30%); blood pressure: n = 5 (0.11%); similar distributions between the 2 groups.
†
Low risk: 1 (men), 2 (women); Moderate risk: 2–3 (men), 3–4 (women); High risk: 4+ (men), 5+ (women).