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. 2023 Aug 3;66(16):11447–11463. doi: 10.1021/acs.jmedchem.3c00959

Table 3. In Vitro Characterization of Compound 9d.

PK parameter		9d
solubility^a		2.14
stability^b	pH 7.4	>24
stability^b	plasma	>24
mouse liver microsomes	T_1/2^c	56
mouse liver microsomes	CL_int^d	123.7
human liver microsomes	T_1/2^c	55
human liver microsomes	CL_int^d	126.7

^a

mM.

^b

h.

^c

min.

^d

μL/min/mg protein.