Table 3.

Multivariate logistic regression analysis of conventional ultrasound and ultrasound elastography indices for predicting the aggressive features of PTC

Characteristic		Capsular invasion			ETE			CLNM
		OR	95% CI	p- value	OR	95% CI	p- value	OR	95% CI	p- value
Sex	Male							Reference
	Female							0.473	0.305,0.733	0.001a
Age								0.969	0.953,0.986	< 0.001a
Size		1.033	0.993,1.074	0.107	1.055	1.017,1.095	0.005a	1.020	0.982,1.058	0.309
Location				0.016a
	Right	Reference
	Left	0.558	0.367,0.830	0.004a
	Isthmus	0.704	0.262,1.890	0.486
Echogenicity				0.052
	Hypo-	Reference
	Hyper-	1.178	0.276,5.026	0.825
	Iso-	0.367	0.161,0.840	0.018
Margin	Clear							Reference
	Unclear							1.630	1.096,2.422	0.016a
CC	No	0.470	0.228,0.793	0.005a
	Yes	Reference
DCE	No	Reference
	Yes	1.404	0.900,2.189	0.134
SCLNM	No				Reference			Reference
	Yes				1.588	0.777,3.245	0.205	2.142	1.198,3.828	0.010a
SWE_tumor_SD								0.992	0.929,1.060	0.821
SWE_ratio					0.778	0.369,1.641	0.510
SWV_tumor_SD		1.221	0.502,2.974	0.695				3.007	0.410,22.053	0.279
SWV_ratio					5.036	0.445,56.992	0.192

PTC = papillary thyroid carcinoma;ETE = extrathyroidal extension; CLNM = cervical lymph node metastasis; OR = odds ratio; CI = confident interval; CC = capsule contact; DCE = discontinuous capsule echo, SCLNM = suspected cervical lymph nodes metastases; SWE_tumor_SD = one standard deviation of shear wave elasticity value of the tumor; SWE_ratio = the ratio of tumor shear wave elasticity value to that of the parenchyma; SWV_tumor_SD = one standard deviation of shear wave speed of the tumor; SWV_ratio = the ratio of tumor shear wave speed to that of the parenchyma.

“a” indicates statistical differences.