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. 2023 Aug 14;14:1224151. doi: 10.3389/fphar.2023.1224151

FIGURE 1.

FIGURE 1

Schema of intrinsic and extrinsic pathways of apoptosis. The extrinsic pathway starts with the stimulation of death receptors followed by activation of caspase-8 and -10. The intrinsic pathway initiates in response to cell damage and continues by activation of caspase-9. Both pathways join in caspase-3 activation, which results in apoptosis.