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The HC-GSSVs located in the CREs of the brain. (A) The HC-GSSV-related genes showing human–chimp-specific CRE activity (by the H3K27ac signals) and gene expression changes (by RNA-seq) compared with macaque across seven brain regions, including CB, CN, OP, PcGm, PFC, Put, and TN. (B) Ranking of the 43 upregulated genes based on gene expression and the H3K27ac signals.
