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. 2023 Aug 24;16:3669–3685. doi: 10.2147/JIR.S420747

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© 2023 Bu et al.

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sHLA-G expression in aGVHD after allo-HSCT.

Notes: (A) The baseline levels of sHLA-G before allo-HSCT regarding as sex, age and disease status groups. (B) The sHLA-G levels in the control group (n = 6), aGVHD group (n = 7) and non-aGVHD group (n = 6) pre-transplantation. (C) The sHLA-G levels between aGVHD group (n = 7) and non-aGVHD (n = 6) group on day +15 after transplantation. (D) The sHLA-G levels between aGVHD group (n = 7) and non-aGVHD (n = 6) group on day +30 after transplantation. (E–G) ROC curve of sHLA-G concentration before transplantation (E), on day +15 (F) and day +30 after transplantation (G) (n = 13). (H) Correlation between sHLA-G level and percentage of Tregs on day +30 after transplantation (n = 13). *p < 0.05, based on the Student’s t-test.

Abbreviations: AML, acute myeloid leukemia; ALL, acute lymphoblastic leukemia; CR, complete remission; NR, non-remission; AUC, area under curve; ns, no significance.