Table 2. Respiratory parameters regardless of IAP model, presented as median values with interquartile ranges and significance.
| Control | IAP 20mmHg | IAP 30mmHg | IAP 40mmHg | p-value | |
|---|---|---|---|---|---|
| n = 5 | n = 19 | n = 15 | n = 10 | ||
| MPP (mmHg) | 5.0 (0.0) | 6.0 (0.0) | 7.0 (1.0) | 8.0 (1.8) | <0.001 |
| Compliance (mL/cmH 2 0) | 18.0 (2.5) | 8.4 (1.9) | 6.3 (2.0) | 6.5 (1.4) | <0.001 |
| pO2 (mmHg) | 355.5 (70.1) | 407.0 (113.0) | 489.0 (187.3) | 371.0 (83.0) | 0.003 |
| VTE (ml) | 290.0 (75.0) | 210.0 (50.0) | 240.0 (50.0) | 275.0 (40.0) | <0.002 |
| pCO2 (mmHg) | 42.2 (5.0) | 47.8 (17.3) | 46.1 (11.5) | 37.0 (11.6) | 0.091 |
| Plateau pressure (cmH 2 0) | 18.0 (3.0) | 27.0 (6.0) | 34.0 (6.8) | 43.0 (10.0) | <0.001 |
| Driving pressure (cmH 2 0) | 17.0 (3.0) | 26.0 (5.0) | 32.0 (7.0) | 42.0 (11.0) | <0.001 |
MPP = mean pulmonary airway pressure; pO2 = arterial partial pressure of oxygen; VTE = expiratory minute volume; pCO2 = arterial partial pressure of carbon dioxide