Skip to main content
[Preprint]. 2024 Aug 8:2023.08.15.553395. Originally published 2023 Aug 15. [Version 2] doi: 10.1101/2023.08.15.553395

Figure 7. Model of endoderm descending hypothesis for midline formation.

Figure 7.

We hypothesize that as the endoderm moves ventrally and the distance between the notochord and endoderm grows, basement membrane from the endoderm may be left behind. This can be compared to a zipper where each side is the basement membrane underlying the endoderm, and when the zipper pull (tip of endoderm) moves downwards, the basement membrane behind it pulls closer together.