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[Preprint]. 2023 Aug 17:2023.08.15.553056. [Version 1] doi: 10.1101/2023.08.15.553056

Figure 4. Dysregulation of PDK1 at protein expression and phosphorylation level for different sexes and timepoints of Alzheimer’s disease.

Figure 4.

(Panel A) Protein expression (log2-FC) of PDK1 for all timepoints and sexes. (Panel B) The auto-phosphorylation (log2-FC) of PDK1 for all timepoints and sexes. (Panel C) Inferred activity score of PDK1 for all timepoints and sexes. (Panel D) Phosphorylation (log2-FC) of known targets of PDK1 for 9 month data. For all plots, the coloring is done to reflect the degree of statistical significance based on z-scores.