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[Preprint]. 2023 Aug 16:2023.08.11.23293967. [Version 1] doi: 10.1101/2023.08.11.23293967

Figure 1. Blood-based biomarkers of Alzheimer’s disease at different visits, among cognitively unimpaired, incident MCI, and incident AD.

Figure 1.

Figure 1.

Panel A: Mean (95%CI) of the biomarker levels (Y-axis) at visits 1, 2, and 3 (X-axis), in cognitively unimpaired, incident MCI, and incident dementia participants. Z-scores of the log-transformed biomarker levels are presented for the convenience of presentation. Blue represents Log10 p-tau181, green represents Log10 NfL, red represents Log10 GFAP, orange represents Log10 Aβ42/Aβ40, and brown represents Log10 P-tau181/Aβ42.

Panel B: Mean (95%CI) of the biomarker pattern scores (Y-axis) at visits 1, 2, and 3 (X-axis), in cognitively unimpaired, incident MCI, and incident dementia participants. Blue represents PCA1, and green represents PCA2.