Table 6.
Bacteria | Samples | MIC % (v/v) | FIC % (v/v) | FIC index | Effect | ||
---|---|---|---|---|---|---|---|
Alone | Combination | ||||||
S. aureus ATCC 29213 | 1/2 | EPEO | 0.25 | 0.125 | 0.5 | 0.656 | Partial synergy |
1/4 | OMEO | 0.5 | 0.0078 | 0.0156 | |||
1/4 | EPEO | 0.25 | 0.0625 | 0.25 | 0.281 | Synergy | |
1/32 | OMEO | 0.5 | 0.0156 | 0.0312 | |||
1/8 | EPEO | 0.25 | 0.3125 | 0.125 | 0.1874 | Synergy | |
1/16 | OMEO | 0.5 | 0.0312 | 0.0624 | |||
1/32 | EPEO | 0.25 | 0.007813 | 0.03125 | 0.156 | Synergy | |
1/8 | OMEO | 0.5 | 0.0625 | 0.125 | |||
1/64 | EPEO | 0.25 | 0.0039 | 0.0156 | 0.2656 | Synergy | |
1/4 | OMEO | 0.5 | 0.125 | 0.25 | |||
1/256 | EPEO | 0.25 | 0.00976 | 0.003907 | 0.5039 | Partial synergy | |
1/2 | OMEO | 0.5 | 0.25 | 0.25 | |||
1/2048 | EPEO | 0.25 | 0.0001220 | 0.00048828 | 0.25 | Synergy | |
1/4 | LBEO | 0.25 | 0.0625 | 0.25 | |||
1/4096 | EPEO | 0.25 | 6.103.10−5 | 0.00024412 | 0.5002 | Partial synergy | |
1/2 | LBEO | 0.25 | 0.125 | 0.5 | |||
1/4 | LBEO | 0.25 | 0.0625 | 0.25 | 0.75 | Partial synergy | |
1/2 | OMEO | 0.5 | 0.25 | 0.5 | |||
| |||||||
E. coli ATCC 25922 | 1/2 | EPEO | 2 | 1 | 0.5 | 0.625 | Partial synergy |
1/8 | OMEO | 6 | 0.75 | 0.125 | |||
1/4 | EPEO | 2 | 0.5 | 0.25 | 0.5 | Synergy | |
1/4 | OMEO | 6 | 1.5 | 0.25 | |||
1/4096 | EPEO | 2 | 0.00048828 | 0.00024414 | 0.50024414 | Partial synergy | |
1/2 | OMEO | 6 | 3 | 0.5 | |||
1/8 | EPEO | 2 | 0.25 | 0.125 | 0.625 | Partial synergy | |
1/2 | LBEO | 1 | 0.5 | 0.5 | |||
1/4 | EPEO | 2 | 0.5 | 0.25 | 0.25195313 | Synergy | |
1/512 | L.BEO | 1 | 0.00195313 | 0.00195313 | |||
1/2 | EPEO | 2 | 1 | 0.5 | 0.50024414 | Partial synergy | |
1/4096 | LBEO | 1 | 0.00024414 | 0.00024414 | |||
1/2 | LBEO | 1 | 0.5 | 0.5 | 0.625 | Partial synergy | |
1/8 | OMEO | 6 | 0.75 | 0.125 | |||
1/2 | LBEO | 1 | 0.25 | 0.25 | 0.5 | Synergy | |
1/4 | OMEO | 6 | 1.5 | 0.25 | |||
1/16 | LBEO | 1 | 0.0625 | 0.0625 | 0.5625 | Partial synergy | |
1/2 | OMEO | 6 | 3 | 0.5 |