Table 3.

Association of disease- and procedure-related factors and surgical site infections in patients undergoing abdominal surgery with intra-abdominal mesh implantation

Overall cohort
	Univariable analysis			Multivariable analysisa
	OR	95% CI	p-value	OR	95% CI	p-value
Emergency hospitalization	2.257	1.582- 3.220	< 0.001	1.787	1.180–2.708	0.006
Previous laparotomy	1.719	1.087–2.720	0.021	1.745	1.058–2.878	0.029
Duration of operation (hours)	1.187	1.089–1.295	< 0.001	1.193	1.085–1.311	< 0.001
Laparotomy	6.753	4.073–11.196	< 0.001	6.167	3.621–10.504	< 0.001
Type of surgery
Upper-GI surgery	0.319	0.076–1.344	0.120	0.375	0.085–1.653	0.195
Bariatric surgery	4.956	2.620–9.375	< 0.001	4.641	2.079–10.359	< 0.001
Hernia surgery	0.153	0.100–0.234	< 0.001	0.165	0.104–0.263	< 0.001
Hepato-biliary surgery	1.558	0.856–2.837	0.147	1.586	0.806–3.121	0.182
Pancreatic surgery	1.555	0.566–4.273	0.392	1.704	0.568–5.112	0.342
Colorectal surgery	2.116	1.463–3.060	< 0.001	1.941	1.292–2.916	0.001
Emergency Surgery	3.223	2.127–4.883	< 0.001	2.510	1.554–4.055	< 0.001
Open abdomen treatment	3.494	1.488–8.207	0.004	2.359	0.919–6.055	0.074
Wound class (1 = reference)
2	4.105	2.546–6.617	< 0.001	4.336	2.614–7.192	< 0.001
3	8.495	4.647–15.528	< 0.001	7.585	3.913–14.703	< 0.001
4	10.153	6.194–16.642	< 0.001	9.408	5.232–16.918	< 0.001
Wound class ≥ 3	4.728	3.351–6.672	< 0.001	3.878	2.574–5.843	< 0.001
Non-polypropylene mesh	1.587	1.114–2.263	0.011	1.818	1.234–2.679	0.003

Uni- and multivariable logistic regression analyses in imputed dataset

OR odds ratio, CI confidence interval, SSI Surgical site infection

^aAdjusted for sex, age, Body Mass Index, and American Society of Anesthesiologists (ASA) Physical Status Classification System score