Table 4.
Association of disease- and procedure-related factors for surgical site infections in patients undergoing abdominal surgery with intra-abdominal mesh implantation
| Laparotomy | Laparoscopy | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariable analysis | Multivariable analysisa | Univariable analysis | Multivariable analysisa, b | |||||||||
| OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | |
| Emergency hosp. | 1.653 | 1.121- 2.438 | 0.011 | 1.549 | 0.974–2.462 | 0.064 | 3.066 | 0.985–9.540 | 0.053 | 3.115 | 1.062–9.138 | 0.039 |
| Previous laparotomy | 1.150 | 0.666–1.986 | 0.615 | 1.298 | 0.709–2.377 | 0.397 | 1.392 | 0.445–4.351 | 0.569 | 1.209 | 0.359–4.075 | 0.759 |
| Duration of operation (h) | 1.067 | 0.970–1.173 | 0.183 | 1.097 | 0.990–1.215 | 0.077 | 1.305 | 0.973–1.751 | 0.076 | 1.225 | 0.902–1.665 | 0.194 |
| Type of surgery | ||||||||||||
| Upper-GI surgery | 0.215 | 0.051–0.912 | 0.037 | 0.262 | 0.059–1.157 | 0.077 | -c | –c | –c | –c | –c | –c |
| Bariatric surgery | 4.037 | 1.966–8.291 | < 0.001 | 2.682 | 1.105–6.511 | 0.029 | 6.964 | 1.339–36.229 | 0.021 | 7.317 | 1.051- 50.924 | 0.044 |
| Hernia surgery | 0.291 | 0.177–0.477 | < 0.001 | 0.294 | 0.172–0.502 | < 0.001 | 0.136 | 0.051–0.364 | < 0.001 | 0.138 | 0.048–0.391 | < 0.001 |
| Hepato-biliary surgery | 1.249 | 0.670–2.329 | 0.484 | 1.423 | 0.698–2.900 | 0.332 | –c | –c | –c | –c | –c | –c |
| Pancreatic surgery | 1.021 | 0.368–2.835 | 0.968 | 1.330 | 0.435–4.062 | 0.617 | –c | –c | –c | –c | –c | –c |
| Colorectal surgery | 1.363 | 0.924–2.013 | 0.119 | 1.356 | 0.883–2.084 | 0.165 | 1.170 | 0.148–9.263 | 0.882 | 1.005 | 0.123- 8.227 | 0.996 |
| Emergency Surgery | 2.174 | 1.360–3.474 | < 0.001 | 2.104 | 1.216–3.641 | 0.008 | 12.433 | 4.496–34.384 | < 0.001 | 14.649 | 4.384- 48.949 | < 0.001 |
| Open abdomen treatment | 2.168 | 0.920–5.111 | 0.077 | 1.672 | 0.650–4.302 | 0.287 | – | – | – | – | – | – |
| Wound class (1 = ref.) | ||||||||||||
| 2 | 2.321 | 1.330–4.050 | 0.003 | 2.567 | 1.424–4.630 | 0.002 | 4.313 | 1.441–12.902 | 0.009 | 4.173 | 1.352- 12.880 | 0.013 |
| 3 | 5.082 | 2.599–9.935 | < 0.001 | 4.566 | 2.204–9.459 | < 0.001 | –c | –c | –c | –c | –c | –c |
| 4 | 5.054 | 2.867–8.909 | < 0.001 | 4.693 | 2.455–8.972 | < 0.001 | 17.889 | 4.542–70.461 | < 0.001 | 21.391 | 4.528- 101.047 | < 0.001 |
| Wound class ≥ 3 | 2.997 | 2.066–4.347 | < 0.001 | 2.555 | 1.656–3.942 | < 0.001 | 5.684 | 1.707–18.928 | 0.005 | 5.944 | 1.573- 22.459 | 0.009 |
| Non-polypropylene mesh | 1.407 | 0.954–2.075 | 0.085 | 1.816 | 1.183–2.785 | 0.006 | 0.785 | 0.222–2.783 | 0.708 | 0.703 | 0.193- 2.558 | 0.592 |
Uni- and multivariable logistic regression analyses in imputed datasets
OR odds ratio, CI confidence interval, SSI Surgical site infection
aAdjusted for sex, age, Body Mass Index, and American Society of Anesthesiologists (ASA) Physical Status Classification System score
bAdjusted for ASA ≥ 3, as no SSI occurred in ASA = 1 group. cNo SSI occurred in investigated group