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. 2023 May 4;44(9):1867–1878. doi: 10.1038/s41401-023-01094-7

Fig. 5. BeG protects against sepsis induced by E. coli.

Fig. 5

a Schematic of the experimental strategy. b Survival of mice intraperitoneally injected with E. coli (1 × 1011 CFU/kg) with or without BeG pre-treatment (50 mg/kg, n = 12 per group). c, d Cytokine (IL-1β, tumor necrosis factor [TNF-α]) concentrations in the serum (n = 5 per group). e–g Representative microscopic pictures of lung, liver and colon H&E staining. h Western blot analysis of the expression of NLRP3, ProCasp1, GSDMD, Casp1-p10, and LC3 protein in the lung. Scale bar 100 μm. Data shown as mean ± SD (***P < 0.001, ****P < 0.0001; ns not significant).