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. 2023 Jul 28;83(13):1179–1205. doi: 10.1007/s40265-023-01916-2
Anti-TNFs seem to be the most effective agents in preventing and treating postoperative recurrence in Crohn’s disease. These agents remain an effective option in patients with anti-TNF failure before surgery.
Vedolizumab seems to be quite effective in the prevention of postoperative recurrence.
Ustekinumab is probably also effective in the postoperative setting, although the comparative efficacy with anti-TNFs or vedolizumab is still unclear.