Table 2.
Estimated Glomerular Filtration Rate Annual Slope Differences for CKD Cohort by COVID-19 Status During the COVID-19 Pandemic.
| Cohort | Overall | COVID-19 | Uninfected | P value |
|---|---|---|---|---|
| Overall cohort | ||||
| Slope differencea (ml/min/1.73m2), median (IQR) | –2.65 (5.26) | –2.94 (5.51) | –2.36 (4.98) | <0.001 |
| Worsenedb, n (%) | 6,751 (75.85) | 3,456 (77.23) | 3,295 (74.44) | 0.002 |
| CKD stage G3a | ||||
| Slope difference (ml/min/1.73m2), median (IQR) | –3.37 (5.10) | –3.65 (5.32) | –3.12 (4.89) | <0.001 |
| Worsened, n (%) | 4,590 (81.72) | 2,354 (82.65) | 2,236 (80.75) | 0.07 |
| CKD stage G3b | ||||
| Slope difference (ml/min/1.73m2), median (IQR) | –1.76 (4.50) | –2.09 (4.82) | –1.36 (4.23) | <0.001 |
| Worsened, n (%) | 1,723 (70.04) | 874 (71.88) | 849 (68.25) | 0.05 |
| CKD stage G4 | ||||
| Slope difference (ml/min/1.73m2), median (IQR) | –0.28 (4.14) | –0.53 (4.44) | –0.08 (3.96) | 0.27 |
| Worsened, n (%) | 438 (53.16) | 228 (55.47) | 210 (50.85) | 0.21 |
Abbreviations: COVID-19, coronavirus disease 2019; CKD, chronic kidney disease; IQR, interquartile range.
a
Mann-Whitney U test.
b
Two-proportions Z-test.