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Pathway of mediation effect of antibiotics exposure in third trimester on respiratory morbidity/atopy. c: direct effect of antibiotics exposure in third trimester on respiratory morbidity/atopy after controlling for microbiome; a×b: indirect effect of antibiotics exposure in third trimester on respiratory morbidity/atopy; c′: total effect of antibiotics exposure in third trimester on respiratory morbidity/atopy (c′=c+a×b).
