Table V.
Arterial ring testing stratified by calcification or flow parameters
| Calcification |
Flow |
|||||
|---|---|---|---|---|---|---|
| None | Present | P value | Stable | Disturbed | P value | |
| Relaxation to MCh | 5 (3) | 47 (6) | .18 | 59 (5) | 2 (4) | .03 |
| Max contraction to KCl, mN | 123 (6) | 112 (8) | .41 | 163 (5) | 90 (9) | .11 |
| Max contraction to PE, mN | 66 (6) | 60 (8) | .4 | 79 (5) | 54 (9) | .14 |
KCl, Potassium chloride; MCh, methacholine; PE, phenylephrine.
Values are number (%).
Relaxation and contraction of human tibial arteries were analyzed and stratified based on calcification status and flow dynamics. Disturbed flow but not calcification significantly decreased maximum relaxation to methacholine of human peripheral arterial disease (PAD) arteries compared with stable flow in no-PAD arteries; however, it had no effect on contraction to potassium chloride or phenylephrine. Statistical testing with one-way analysis of variance. Significance defined as P < .05 and significant values bolded.