Table 1.

Hydrogel dressings for diabetic wounds in completed or ongoing clinical trials from the National Library of Medicine

Hydrogel dressing	Conditions or diseases	Clinical phases	Status	Clinical trials numbers	Date	Marketed
AmeriGel®	Type 1 diabetes; Type 2 diabetes; DFUs	4	Terminated (study closed due to recruitment problems)	NCT01350102	2012.04–2014.03	No
Fitostimoline® hydrogel	Diabetic foot	4	Completed	NCT05661474	2021.02–2022.12	Yes
SANTYL®	DFUs; Diabetic foot wounds	4	Completed	NCT02111291	2014.04–2015.12	Yes
Woulgan Gel	DFU	4	Completed	NCT02631512	2015.10–2019.04	Yes
ALLO-ASC-DFU (hydrogel sheet containing allogenic mesenchymal stem cells)	DFU	1	Completed	NCT03183726	2016.01–2017.07	No
Hydrogel Purilon®	Diabetic foot; Diabetic Neuropathy; Foot ulcer	2	Completed	NCT03700580	2012.08–2016.10	No
IZN-6D4 Gel	DFU	2	Completed	NCT01427569	2012.03–2015.08	No
Lavior Diabetic Wound Gel	DFU	2	In progress	NCT05607979	2022.12–2023.06	No
NanoDOX™ Hydrogel	DFU	2	Completed	NCT00764361	2009.01–2010.08	No
TWB-103 (mixture of TWB-102 cell and TWB-103 hydrogel)	DFU	1/2	Unknown	NCT03624023	2019.12–2021.07	No
Hydrogel with 3% sodium pentaborate pentahydrate	Wound healing	1	In progress	NCT02241811	2014.09–2023.12	No
RMD-G1 (a hydrogel containing erythropoietin)	DFU	1	Completed	NCT02361931	2016.03–2018.06	No
Cadexomer iodine gel	DFU	Not applicable	Terminated (recruitment challenges)	NCT02181621	2014.08–2015.10	No
Hydrogel/nano silver-based dressing	Diabetes mellitus	Not applicable	Completed	NCT04834245	2019.01–2019.12	No
Regranex®	DFU	Not applicable	Unknown	NCT00446472	2007.04–2010.09	No
Solosite gel	DFU	Not applicable	Terminated	NCT02181621	2014.08–2015.10	No
ConvaTec DuoDERM Hydroactive Gel	DFU	Not applicable	Completed	NCT00971048	2009.09–2011.01	No

ASC allogenic mesenchymal stem cells, DFU diabetic foot ulcer, NCT National Clinical Trial