Table 2.
Clinical characteristics and islet function indexes of total subjects according to GAD values
| LADA-1 | LADA-2 | P | |
|---|---|---|---|
| GAD(IU/ml) | ≥ 180 | < 180 | |
| n | 136 | 351 | |
| male (%) | 66(48.5%) | 164(46.7%) | 0.139 |
| Age (years) | 58.8 ± 16.3 | 58.1 ± 15.2 | 0.741 |
| duration(years) | 6.7 ± 4.4 | 7.0 ± 4.3 | 0.115 |
| BMI (kg/m2) | 19.4 ± 4.3 | 23.6 ± 4.2 | 0.034 |
| SBP (mmHg) | 127.8 ± 17.3 | 128.9 ± 18.7 | 0.259 |
| DBP (mmHg) | 70.5 ± 16.7 | 71.2 ± 18.6 | 0.395 |
| TG (mmol/L) | 1.4 ± 0.7 | 1.6 ± 0.6 | 0.017 |
| TC (mmol/L) | 4.3 ± 0.8 | 4.4 ± 0.9 | 0.085 |
| LDL (mmol/L) | 2.6 ± 0.6 | 2.7 ± 0.7 | 0.033 |
| HDL (mmol/L) | 1.0 ± 0.4 | 1.0 ± 0.5 | 0.096 |
| GAD(IU/ml) | 272.0 ± 62.7 | 57.2 ± 54.3 | < 0.001 |
| ALT (U/L) | 19.7 ± 12.7 | 21.2 ± 13.6 | 0.329 |
| AST (U/L) | 19.8 ± 13.1 | 20.5 ± 12.8 | 0.413 |
| Cr (umol/L) | 64.9 ± 30.2 | 63.5 ± 29.7 | 0.154 |
| SUA (umol/L) | 324.2 ± 145.8 | 323.7 ± 151.3 | 0.469 |
| HbA1c(%) | 9.4 ± 2.4 | 9.1 ± 2.1 | 0.024 |
| FCP (ng/ml) | 1.0 ± 0.7 | 1.7 ± 0.7 | 0.013 |
| P2hCP (ng/ml) | 1.7 ± 0.8 | 2.4 ± 0.8 | 0.012 |
| Use of insulin(%) | 88(64.7%) | 136(38.7%) | < 0.001 |
| HOMA-IR | 1.6 ± 0.6 | 1.7 ± 0.6 | 0.079 |
| HOMA-β | 11.0 ± 5.7 | 14.7 ± 6.3 | 0.019 |
Values are mean ± SD.