Table 2.
Baseline characteristics stratified by the four groups
| Variables | HsCRP-L/non-DM (n = 4417) | HsCRP-H/non-DM (n = 1189) | HsCRP-L/DM (n = 1898) | HsCRP-H/DM (n = 546) | P value |
|---|---|---|---|---|---|
| Age, years | 58.0 ± 10.3 | 58.6 ± 10.7 | 59.1 ± 9.5 | 59.3 ± 9.9 | < 0.001 |
| Male | 3427 (77.6) | 906 (76.2) | 1446 (76.2) | 387 (70.9) | 0.005 |
| Body mass index, kg/m2 | 25.6 ± 3.1 | 26.3 ± 3.3 | 26.1 ± 3.1 | 26.9 ± 3.3 | < 0.001 |
| Previous history | |||||
| Hypertension | 2706 (61.3) | 751 (63.2) | 1290 (67.0) | 408 (74.7) | < 0.001 |
| Hyperlipidemia | 2838 (64.3) | 750 (63.1) | 1401 (73.8) | 411 (75.3) | < 0.001 |
| Current smoking | 2484 (56.2) | 717 (60.3) | 1021 (53.8) | 309 (56.6) | 0.006 |
| Previous stoke | 368 (8.3) | 133 (11.2) | 234 (12.3) | 81 (14.8) | < 0.001 |
| Previous PAD | 304 (6.9) | 75 (6.3) | 186 (9.8) | 55 (10.1) | < 0.001 |
| Clinical history | |||||
| Previous PCI | 1057 (23.9) | 213 (17.9) | 526 (27.7) | 126 (23.1) | < 0.001 |
| Previous CABG | 175 (4.0) | 44 (3.7) | 89 (4.7) | 31 (5.7) | 0.143 |
| Previous MI | 905 (20.5) | 192 (16.1) | 399 (21.0) | 91 (16.7) | 0.001 |
| Clinical presentation | < 0.001 | ||||
| ACS | 2473 (56.0) | 794 (66.8) | 1012 (53.3) | 319 (58.4) | |
| CCS | 1944 (44.0) | 395 (33.2) | 886 (46.7) | 227 (41.6) | |
| Laboratory | |||||
| hsCRP, mg//L | 1.06 (0.60–1.69) | 4.66 (3.62–6.63) | 1.10 (0.65–1.81) | 4.56 (3.60–6.38) | < 0.001 |
| HbA1c, % | 6.06 ± 0.58 | 6.18 ± 0.73 | 7.68 ± 1.36 | 7.98 ± 1.41 | < 0.001 |
| Creatinine, mmol/L | 74.7 ± 14.2 | 76.5 ± 17.0 | 74.3 ± 15.8 | 75.8 ± 18.8 | < 0.001 |
| LDL, mmol/L | 2.47 ± 0.90 | 2.70 ± 0.94 | 2.36 ± 0.87 | 2.56 ± 0.91 | < 0.001 |
| LVEF, % | 63.7 ± 6.9 | 62.7 ± 7.3 | 63.2 ± 7.0 | 62.8 ± 7.2 | < 0.001 |
| Drug therapy | |||||
| Aspirin | 4367 (98.9) | 1170 (98.4) | 1884 (99.3) | 537 (98.4) | 0.103 |
| Clopidogrel | 4351 (98.5) | 1166 (98.1) | 1871 (98.6) | 542 (99.3) | 0.285 |
| Beat-blocker | 3943 (89.3) | 1056 (88.9) | 1751 (92.3) | 496 (90.8) | 0.001 |
| Statins | 4259 (96.4) | 1140 (95.9) | 1807 (95.2) | 528 (96.7) | 0.116 |
| DAPT | 4304 (97.4) | 1150 (96.7) | 1858 (97.9) | 535 (98.0) | 0.195 |
| PCI-related data | |||||
| Multivessel disease | 3148 (71.3) | 904 (76.0) | 1565 (82.5) | 457 (83.7) | < 0.001 |
| LM stenosis | 270 (6.1) | 61 (5.1) | 137 (7.2) | 42 (7.7) | 0.058 |
| SYNTAX score | 9.0 (5.0–15.5) | 10.0 (6.0–17.0) | 10.0 (6.0–17.0) | 11.0 (6.0–17.5) | < 0.001 |
| TIMI 0 before PCI | 647 (14.6) | 231 (19.4) | 309 (16.3) | 101 (18.5) | < 0.001 |
| Number of stents | 1 (1–2) | 2 (1–2) | 2 (1–2) | 2 (1–2) | < 0.001 |
Abbreviations as in Table 1