Table 2.

Outcomes Patients with Heart Failure with Preserved Ejection Fraction ≥50% and Heart Rate ≥70 Beats/Minute, by High-Dose Beta-Blocker Versus No Beta-Blocker Use

	Events (%)
	No beta-blocker (n=640)	High-dose beta-blocker (n=640)	Hazard ratio* (95% confidence interval)
All-cause mortality	438 (68%)	403 (63%)	0.86 (0.75–0.98); p=0.027
All-cause readmission	566 (88%)	565 (88%)	0.90 (0.81–1.02); p=0.100
Heart failure readmission	294 (46%)	287 (45%)	0.93 (0.79–1.09); p=0.362
All-cause readmission or all-cause mortality	619 (97%)	607 (95%)	0.89 (0.80–1.00); p=0.044
Heart failure readmission or all-cause mortality	522 (82%)	496 (78%)	0.90 (0.80–1.02); p=0.091

^*Associated with high-dose beta-blocker use