Fig. 3.

Difference of miRNA biomarker expression levels between T2DM and HC group. We derived miRNA biomarker set using each setting for feature selection. We compared miRNA expression levels between T2DM and HC groups. A Settings 5 (the best setting), (B) 1, (C) 2, (D) 3, (E) 4, and (F) 6 were configured based on miRDM-rfGA. G Setting 7, and (H) settings 8 and 9 were configured using traditional feature selection methods (F-test and Lasso). The same miRNAs were selected in settings 8 and 9. Each miRNA expression was converted into z-score