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. 2023 Aug 22;16:195. doi: 10.1186/s12920-023-01636-2

Fig. 4.

Fig. 4

The best miRNA biomarker set in setting 5. A Principal Component Analysis (B) Functional enrichment analysis of the miRNA biomarker set. C Pathway of IRS-related events triggered by IGF1R signaling. DE analysis result of the best miRNA biomarker set and the targeted mRNAs in skeletal muscle. The circle size of each point is proportional to the |log2 of fold change in T2DM vs. healthy control|