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Anti-inflammatory effect of KYP-2047. Western blot analysis showed an important modulation of IκBα/NF-κB pathway (respectively B and A). Additionally, treatments with KYP-2047 reduced COX-2 (C), iNOS (D) and TNF-α (E) expression compared to the BLM group. Data are representative of at least three independent experiments. One way ANOVA test ***p < 0.001 vs Sham; #p < 0.05 vs BLM; ##p < 0.01 vs BLM; ###p < 0.001 vs BLM
