Skip to main content
. 2023 Aug 26;21:575. doi: 10.1186/s12967-023-04432-9

Table 1.

Variation of biometric and physiological parameters in different treatment rats

Group Body weight (g) Ventral prostate weight (mg) Seminal vesicles weight (mg) Prostate index
Initial Final
Con 267.4 ± 15.6 451.4 ± 24.3 597.2 ± 94.8 1144.1 ± 165.0 1.3 ± 0.2
T 259.8 ± 17.2 383.6 ± 17.8*** 1028.9 ± 94.6*** 2524.0 ± 288.6 2.7 ± 0.2***
T + RSL3 266.1 ± 15.7 335.9 ± 23.4Inline graphic 572.1 ± 102.9Inline graphic 1337.0 ± 118.4 1.7 ± 0.3Inline graphic
T + TRO 263.3 ± 14.8 429.1 ± 23.1Inline graphic 711.9 ± 83.7Inline graphic 1282.9 ± 187.6 1.7 ± 0.3Inline graphic
T + RSL3 + TRO 264.4 ± 16.2 408.7 ± 21.5Inline graphic 539.3 ± 53.6 ns 1276.9 ± 164.8 1.3 ± 0.2 Inline graphic

T testosterone; RSL3 RAS-selective lethal 3; TRO troglitazone

***p < 0.001 Con vs. T

Inline graphicp < 0.01 T vs. T + RSL3; Inline graphicp < 0.001 T vs. T + RSL3

Inline graphicp < 0.01 T vs. T + TRO; Inline graphicp < 0.001 T vs. T + TRO;

Inline graphicp < 0.05 T + RSL3 vs. T + RSL3 + TRO; Inline graphicp < 0.001 T + RSL3 vs. T + RSL3 + TRO

ns p > 0.05 T + RSL3 vs. T + RSL3 + TRO