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. 2023 Aug 29;21:79. doi: 10.1186/s12958-023-01126-1

Table 1.

Formulated question of the study based on PICOS

Inclusion criteria
P(Participants) Endometriosis patient
I(Intervention) Vitamin C/E/D with no limits on the dose,frequency and so on
C(Comparisons) No supplementation or placebo
O(Outcomes)

Primary:chronic pelvic pain,dysmenorrhea,dyspareunia;

Secondary outcome: oxidative stress markers,fertility

S(Study type) Randomized controlled trials(RCTs)