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. 2023 Aug 29;24:496. doi: 10.1186/s12864-023-09601-0

Table 2.

Genome-wide significant locus (P < 5 × 10–8) associated with eGFR after meta-analysis

UKBB MVP CKDGen Meta-analysis Replication (Uganda)
Locus Lead SNP Chr BP(b37) EA/NEA N MAF P N MAF P P N Zscore Direction N SNP MAF P
ELN rs77408001 7 73,443,012 C/A 6217 0.006693 0.03198 57,736 0.0135 7.283e-08 NA 7.264e-09 63,553 -5.210  −  −  5877 7:73,727,705 0.01 8.85e-04

SNP Single nucleotide polymorphism, Chr Chromosome, BP Base position, NEA Non-effect allele, SE Standard error, NA Not available