Urease Inhibition Activity of Compounds (5–32).
| |||||
|---|---|---|---|---|---|
| Compd | R | IC50 ± SEM (μM) | Compd | R | IC50 ± SEM (μM) |
| 5 |
|
39 ± 1.2 | 19 |
|
16 ± 0.3 |
| 6 |
|
20 ± 0.5 | 20 |
|
12 ± 0.9 |
| 7 |
|
16 ± 0.1 | 21 |
|
13 ± 0.2 |
| 8 |
|
41 ± 1.2 | 22 |
|
31 ± 1.4 |
| 9 |
|
72 ± 1.2 | 23 |
|
37 ± 1.4 |
| 10 |
|
20 ± 0.5 | 24 |
|
13 ± 0.1 |
| 11 |
|
41 ± 1.2 | 25 |
|
35 ± 1.5 |
| 12 |
|
74 ± 1.3 | 26 |
|
12 ± 0.1 |
| 13 |
|
16 ± 0.9 | 27 |
|
34 ± 2.4 |
| 14 |
|
35 ± 1.2 | 28 |
|
14 ± 0.3 |
| 15 |
|
31 ± 1.2 | 29 |
|
41 ± 1.4 |
| 16 |
|
13 ± 0.2 | 30 |
|
12 ± 0.1 |
| 17 |
|
36 ± 1.2 | 31 |
|
15 ± 0.3 |
| 18 |
|
38 ± 1.4 | 32 |
|
15 ± 0.3 |
| Thiourea 22 ± 2.2 μM | |||||