Skip to main content
. Author manuscript; available in PMC: 2023 Aug 29.
Published in final edited form as: ACS Chem Biol. 2022 Jul 5;17(7):1714–1722. doi: 10.1021/acschembio.1c00961

Figure 3. Evaluation of FQ.

Figure 3.

(a,b) Purified oCOX-1 and mCOX-2 isozyme inhibition by FQ and FQ-H, respectively; (c,d) cell-based (1483 HNSCC cells) COX-2 inhibition by FQ and FQ-H, respectively; (e-f) 1483 HNSCC cells were treated with FQ followed by fluorescence microscopy at 0.5 h and 3 h post-incubation; (g) cell fluorescence was measured on a BioTek Synergy MX Plate Reader, and Welch’s correction was performed for an unpaired parametric t test performed to assess statistical difference, where the error bars represent standard error.