Table 1.
Diagnostic categories (modified from WHO 5th ed. classification).
| 1 | Benign breast | Normal (non-atypical) breast parenchyma | Normal breast Inflammatory change Radiation change |
|---|---|---|---|
| Benign (non-atypical) epithelial proliferations | Fibrocystic changes Columnar cell change Sclerosing adenosis Mucocele-like lesion without atypia | ||
| 2 | Radial scar without atypia | ||
| Radial scar with atypia / complex sclerosing lesion | |||
| 3 | Flat epithelial atypia (FEA) (columnar cell change with atypia) | ||
| 4 | Classic lobular carcinoma in situ (cLCIS) Atypical lobular hyperplasia (ALH) | ||
| 5 | Pleomorphic / florid LCIS | ||
| 6 | Atypical ductal hyperplasia (ADH) | ||
| 7 | Ductal carcinoma in situ (DCIS) | ||
| 8 | Microinvasive carcinoma (mIC) | ||
| 9 | Invasive breast carcinoma (IBC) (any type) | ||
| 10 | Papilloma | Without atypia | |
| With ADH | |||
| With DCIS | |||
| 11 | Papillary carcinoma | Without invasion | Encapsulated papillary carcinoma (EPC) w/o invasion Solid papillary carcinoma (SPC) in situ |
| With microinvasion | EPC with mIC SPC with mIC |
||
| Invasive | Invasive papillary carcinoma Invasive SPC IBC near EPC or SPC |
||
| 12 | Fibroadenoma | ||
| 13 | Fibroepithelial lesion (not specified as fibroadenoma) Phyllodes tumor |
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