Table II.

Mean (SD) scores for each research agenda item from the symposium delegates (n = 31). Bolded items met the prespecified criteria of ≥ 70

	Item	Mean (SD)
Diagnosis	1. Develop an overarching clinical definition of foot and ankle OA	82.6 (21.3)
	2. Develop clinical diagnostic criteria for midfoot and ankle OA	85.9 (10.4)
	3. Evaluate first MTPJ OA diagnostic criteria in a larger cohort and a range of forefoot conditions	66.4 (22.7)
	4. Develop foot OA MRI scoring systems	65.4 (19.1)
	5. Explore the relationship between observable features on MRI and symptoms, disease progression and treatment response	71.2 (21.9)
Epidemiology	6. Develop consensus on the components of pain variables to be included in the definition of symptomatic OA (i.e., descriptors, duration, location)	75.9 (25.5)
	7. Develop criteria to document radiographic progression	74.7 (20.4)
	8. Determine whether ankle OA is a separate entity to foot OA	70.2 (23.5)
	9. Identify whether foot and ankle OA phenotypes change over time	73.7 (17.3)
Burden	10. Examine progression of foot and ankle OA and mechanical function through longitudinal investigations in diverse populations	74.4 (20.0)
	11. Advance the understanding of consequent effects of early, mid and late-stage ankle OA and midfoot OA on mechanical function using gait analysis with 3D kinematics	64.4 (18.8)
	12. Clarify differences between health-related quality of life among those with and without foot and ankle OA	74.9 (24.8)
	13. Determine subgroup-specific approaches to improve health-related quality oflife related to foot and ankle OA	74.2 (18.0)
	14. Quantify the economic and societal burden of foot and ankle OA	85.3 (16.7)
Outcome assessment	15. Work parallel with OMERACT to develop an agreed, standardised core outcome set for foot and ankle OA, including patient-reported outcome measures, physical function and structural measures	82.3 (27.5)
	16. Further evaluate the measurement properties of existing patient-reported outcome measures for foot and ankle OA	75.4 (22.9)
	17. Development of new foot and ankle OA-specific patient-reported outcome measures	64.2 (28.0)
	18. Further validation of ultrasound and MRI imaging-specific outcome measures to assess inflammatory features and structural damage in foot and ankle OA	70.0 (24.3)
Treatment	19. Ascertain what usual care is for foot and ankle OA so it can be used as the comparator in clinical trials	82.9 (15.6)
	20. Identify appropriate placebos/shams for use in clinical trials	69.2 (21.1)
	21. Evaluate the efficacy of exercise in the treatment of foot and ankle OA	82.8 (18.7)
	22. Evaluate the efficacy of weight loss in the treatment of foot and ankle OA	74.0 (22.7)
	23. Evaluate the efficacy of orthoses and footwear in the treatment of foot and ankle OA	79.1 (19.3)
	24. Develop models of care for foot and ankle OA that can be implemented in general practice	88.4 (11.5)