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. Author manuscript; available in PMC: 2023 Aug 29.
Published in final edited form as: J Am Coll Cardiol. 2019 Aug 6;74(5):617–627. doi: 10.1016/j.jacc.2019.05.064

Central Illustration: Kaplan-Meier Plots for Outcomes by Digoxin Discontinuation.

Central Illustration:

This study assessed the relationship of discontinuation of chronic digoxin therapy with heart failure readmission (top panel) and all-cause mortality (middle panel) in 698 pairs of propensity score-matched patients with heart failure with reduced ejection fraction. During 4 years of follow-up, digoxin discontinuation was associated with a significantly higher risk of all outcomes, compared with patients whose chronic digoxin therapy was continued. CI = confidence interval; HR = hazard ratio.