TABLE 2.

Potential clinical relevance of preclinical model

	Relevance of model			Relevance of illness		Relevance of therapy
Author, year	Adult	Comorbidities	Size	>2 h of cold ischemic time	Hetero (vs auto) transplant	Therapy initiated before retrieval	CNI dose analogous to usual	Adequate supportive care
								Donor	Recipient
Kidney
Abbasi Dezfouli, 202037	⦸	⊗	⊕	⊕	⊕	⊕	⊕	⊕	⊕
Cicora, 201238	⦸	⊗	⊗	⊕	⊗	⊕	⊕	⊕	⊗
Cicora, 201123	⦸	⊗	⊗	⊕	⊕	⊕	⊕	⊕	⊗
Martinez-Pilli, 201139	⦸	⊗	⊗	⊕	⊕	⊕	⊕	⊕	⦸
Cicora, 201040	⦸	⊗	⊗	⊕	⊕	⊕	⊕	⦸	⦸
Shihab, 201041	⊕	⊗	⊗	⊕	⊕	⊕	⊗	⊕	⊗
Shihab, 200925	⊕	⊗	⊗	⊕	⊕	⊕	⊗	⊕	⊗
Reutze-Selke, 200342	⊕	⊗	⊗	⊕	⊕	⊕	⦸	⊕	⦸
Liver
Tarrab, 201243	⊕	⊗	⊗	⊕	⊕	⊕	⊕	⊕	⊗
Hüser, 200944	⦸	⊗	⊗	⊕	⊕	⊕	⊗	⦸	⦸
Sasaki, 200445	⦸	⊗	⊗	⊕	⊕	⊕	⦸	⊕	⊗
Kawano, 199646	⦸	⊗	⊗	⊕	⊕	⊕	⊗	⦸	⦸
Yamanoi, 199447	⊕	⊗	⊕	⊕	⊕	⊕	⦸	⊕	⊕
Goto, 199148	⦸	⊗	⊗	⊕	⊕	⊕	⊗	⦸	⊕
Lung
Bayer, 201349	⦸	⊗	⊗	⊕	⊕	⊕	⦸	⊕	⦸
Bowel
Oltean, 200750	⦸	⊗	⊗	⊕	⊕	⊕	⊕	⦸	⦸
Oltean, 200651	⦸	⊗	⊗	⊕	⊕	⊕	⊕	⦸	⦸
Oltean, 200524	⦸	⊗	⊗	⊕	⊕	⊕	⊕	⦸	⦸

CNI, calcineurin inhibitor; ⊕, yes; ⊗, no; ⦸, unclear.