TABLE 3.
Summary of patients with reported cases of G. morbillorum endocarditis and features of our two patients with G. morbillorum endocarditisa
| Patient no./age (yr)/sexa | Underlying conditions or source of infection | Infected valve | Therapy | Valve replacement | Outcome | Reference, year |
|---|---|---|---|---|---|---|
| 1/60/m | Dental manipulation | NA | Penicillin, rifampin | No | Cure | 12, 1984 |
| 2/38/m | Anal subcutaneous sphincterotomy, sigmoidoscopy | Mi | Benzylpenicillin, gentamicin, erythromycin | No | Cure | 35, 1989 |
| 3/39/m | Dental manipulation, bicuspid aortic valve | Ao | Benzylpenicillin, gentamicin | Yes | Cure | 35, 1989 |
| 4/42/m | Mi regurgitation | Mi | Benzylpenicillin, streptomycin | No | Cerebral mycotic aneurysm, cure | 10, 1990 |
| 5/19/m | Intravenous drug abuser | Tri | Flucloxacillin, benzylpenicillin, gentamicin | No | Cure (?; reduction in the size of vegetation) | 6, 1992 |
| 6/48/m | Poor dentition, systolic heart murmur, end-stage renal disease | Mi | Vancomycin | No | Wrist arthritis, cure | 40, 1993 |
| 7/64/m | Dental manipulation | Mi, Ao | Benzylpenicillin | Yes | Acute appendicitis, cure | 45, 1994 |
| 8/29/f | Hypertrophic obstructive cardiomyopathy, dental manipulation | Na | Benzylpenicillin, gentamicin, erythromycin, rifampin | No | Cure | 29, 1994 |
| 9/74/m | Left colonic resection for rectal neoplasia | Tri | Cefuroxime, amikacin, benzylpenicillin | No | Pulmonary embolism, cure | 1, 1995 |
| 10/75/m | Rheumatic fever in infancy | Mi | Benzylpenicillin, gentamicin, teicoplanin, rifampin, erythromycin | No | Allergic reaction to antimicrobial agents, cure | 33, 1995 |
| 11/74/m | Poor dentition, chronic ethylism | Aob | Amoxicillin, gentamicin | Yes | Cure | Patient 2 |
| 12/NA/m | Bicuspid aortic valve | Ao | NA | NA | NA | Patient 3 |
Abbreviations: Ao, aortic valve; Mi, mitral valve; Tri, tricuspid valve; NA, not available; m, male; f, female.
No evidence of vegetation on echocardiogram.