Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Aug 6;13(13):4449–4468. doi: 10.7150/thno.84710

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The author(s)

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

Evaluation of cross-reaction with peptides from MAGE-A12 and Titin by candidate TCRs. (A) Summary of the predicted top 5 HLA-A2 restricted T cell epitopes from MEGA-12 and Titin protein. (B) Heatmap visualization of the docking prediction results between the 5 candidate TCRs and HLA-A2 presenting distinct epitopes. Color intensity represents different docking stability score, with darker colors indicating higher score and suggesting more stable pMHC-TCR complex. (C) The simulated pMHC-TCR complex docking structure of the 5 candidate TCR with MAGE-A3-Mp4: the top part is the structure of TCR and the bottom is the structure of HLA-A2 presenting the MAGE-A3-Mp4 peptide.

HHS Vulnerability Disclosure