Table 2. Baseline characteristics, tumour molecular markers and post-operative management of patients undergoing primary glioblastoma (GBM) resection.
Patient characteristics | White light (n = 189) | 5-ALA (n = 50) |
Age (median) | 60 | 58 |
Sex | Female: 88 (46.6%) | Female: 17 (34.0%) |
Male: 101 (53.4%) | Male: 33 (66.0%) | |
Pre-operative PS | PS ≤ 1: 126 (66.7%)a | PS ≤ 1: 42 (84.0%) |
PS ≥ 2: 60 (31.7%)a | PS ≥ 2: 8 (16.0%) | |
Pre-operative deficit | 174 (92.0%) | 44 (88.0%) |
Tumour molecular markers | White light (n = 189) | 5-ALA (n = 50) |
MGMT methylated | 86 (45.5%) | 18 (36.0%)b |
IDH 1/2 mutation | 17 (9.0%) | 2 (4.0%)c |
Post-operative treatment | White light (n = 189) | 5-ALA (n = 50) |
Radiotherapy | 139 (73.5%)d | 40 (80.0%) |
Chemotherapy | 134 (70.9%)e | 41 (82.0%) |