Table 1.
Characteristics of cohort
| Characteristic | Controls | Cases | p value |
|---|---|---|---|
| Sample size | 28 | 22 | – |
| Age (avg, range) | 29 (21–49) | 34 (23–62) | 0.049 |
| Baseline cytology result (n, %) | 0.512 | ||
| ASCUS | 8 (28.6) | 4 (18.2) | |
| ASC-H | 2 (7.1) (53.7) | 2 (9.1) | |
| LGSIL | 15 (0) | 10 (45.5) | |
| LGSIL + H | 0 (0) | 1 (4.6) | |
| HGSIL | 0 (0) | 1 (4.6) | |
| HR HPV test (n, %) | 1.00 | ||
| Result available | 14 (50) | 11 (50) | |
| Positive | 14 (100) | 11 (100) | |
| P16 staining result (n, %) | – | ||
| Result available | – | 12 (54.5) | |
| Positive | 12 (100) | ||
| Time to resolution (months) | – | ||
| 2nd normal test result (avg, SEM) | 28 (5.3) | – | |
| Total observation period (avg, SEM) | 39 (7.4) | ||
| Time to progression (months, avg, SEM) | – | 21 (4.4) | – |
Bold font indicates statistical signifance p ≤ 0.05
Missing results: Baseline cytology, 4 (2 controls, 2 cases); HPV test, (14 controls, 11 cases); HGCIN p16 staining, 10. Reasons for missing results include the test was not done or the test was performed at a different clinical site and results were not recorded in the EMR. Unpaired t-test was used to compare difference in mean age. Cytology and HPV test were compared as categorical variables by Chi square and Fisher’s Exact test (significance, p < 0.05)