Fig. A1.

T2 maps and corresponding Dixon FF maps of a subject with lower and a subject with higher muscle tissue FF (patient 1, mean FF ​= ​4.9%; patient 2, mean FF ​= ​13.1%). In subject 2 with higher FF, T2 values are elevated, particularly in the vendor-provided T2 map, but also in the mono-exponentially fitted T2 map. In contrast, T2 values were similar for both patients in the tri-exponential T2 map. Moreover, within the thigh muscle of subject 1, a variation could be observed between individual muscles in the product T2 map, which was not present in the custom-fit T2 maps.