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. 2023 Aug 29;6(8):e2331168. doi: 10.1001/jamanetworkopen.2023.31168

Table 2. Incidence of Sepsis According to Different Sepsis Definitionsa.

Parameter Patients, % (95% CI)
Sepsis-3 R-code sepsis Explicit sepsisb Implicit, including explicit sepsis
Cumulative incidencec 4.1 (3.6-4.5) 0.2 (0.2-0.2) 1.0 (1.0-1.1) 1.4 (1.4-1.5)
Annualized incidence-rate per 100 000 person-years 747 (663-832) 46 (32-58) 287 (241-335) 401 (362-440)
a

The calculated incidence among hospitalized patients for Sepsis-3 reference standard and different International Statistical Classification of Diseases and Related Health Problems, Tenth Revision–code abstraction strategy in 2019.

b

Explicit sepsis includes A- and R-sepsis.

c

Cumulative incidence was calculated through weighted frequency.