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. Author manuscript; available in PMC: 2023 Aug 30.
Published in final edited form as: Behav Brain Res. 2019 Nov 22;379:112379. doi: 10.1016/j.bbr.2019.112379

Figure 3.

Figure 3.

Ethological variables related to anxiety-like behavior following administration of KOR activation on the EPM in male and female adolescents (left) and adults (right). Animals were given an i.p. injection of KOR agonist U69593 (0.01, 0.1, or 1 mg/kg) or vehicle, and anxiety was tested 20 min following injection. There was a significant overall difference between adults and adolescents (not indicated). (A, B) Total number of unprotected head dips; (C, D) total number of stretch attend postures. * p < 0.05 for main effect of dose in females only.