Table 1.
Summary statistics and indoor protective efficacy of Mosquito Shield™ in reducing human landings and blood-feeding of wild pyrethroid-resistant An. arabiensis
| Experiment | Intervention | 1Total captured |
2William’s Mean (95% CI) |
3IRR (95% CI) | 4PE (95% CI) | p-value |
|---|---|---|---|---|---|---|
| HLC | Control | 16,392 | 53.8 (50.0, 57.8) | – | – | < 0.0001 |
| Mosquito Shield™ | 5591 | 14.8 (13.2, 16.7) | 0.30 (0.22, 0.43) | 70 (57, 78) | ||
| Feeding | Control | 195 | 2.0 (1.7, 2.2) | – | – | < 0.0001 |
| Mosquito Shield™ | 61 | 1.5 (1.2, 1.7) | 0.31 (0.21, 0.44) | 69 (56, 79) | ||
| Resting | Control | 48 | 0.24 (0.15, 0.33) | – | – | P = 0.001 |
| Mosquito Shield™ | 21 | 0.11 (0.06, 0.17) | 0.39 (0.22, 0.68) | 61 (32, 78) |
1Total captured refers total number of An. arabiensis that landed on participants during the HLC experiment and total number of blood-fed collected from the feeding experiment; 2Average caught per night per hut estimated as geometric mean due to skewness of mosquito count data; 3Incidence rate ratio (IRR) for intervention is reported from generalized negative binomial mixed effect model of mosquito landings/blood-fed adjusted for the effect of volunteer, hut location and study night. 4PE = Protective efficacy ((1-IRR) * 100); for landing inhibition is the percentage reduction in mosquito lands while for blood-feeding inhibition is the percentage reduction in number of blood-fed mosquitoes in the intervention relative to the control