Table 2.
Age- and sex-adjusted baseline concentrations of cardiovascular risk markers
| KAROLA-I | KAROLA-II | ||||
|---|---|---|---|---|---|
| Year 1999/2000 | Year 2009–2011 | ||||
| (n = 1130) | (n = 860) | ||||
| Marker | n | Geometric Mean | n | Geometric Mean | p-valuea |
| Total cholesterol (mg/dL) | 1130 | 166.6 | 859 | 148.2 | < 0.001 |
| LDL-cholesterol (mg/dL) | 1130 | 96.8 | 860 | 85.8 | < 0.001 |
| Cystatin C (mg/L) | 1129 | 1.1 | 860 | 1.0 | < 0.001 |
| hs-CRP (mg/L) | 1129 | 3.5 | 860 | 2.2 | < 0.001 |
| hs-cTnT (ng/L) | 1130 | 13.9 | 860 | 11.5 | < 0.001 |
| hs-cTnI (ng/L) | 1112 | 16.5 | 859 | 11.6 | < 0.001 |
| NT-proBNP (ng/L) | 1130 | 577.4 | 860 | 390.4 | < 0.001 |
| GDF-15 (ng/L) | 1128 | 1314.5 | 849 | 1164.0 | < 0.001 |
Values are reported as age- and sex-adjusted geometric means
aGeneralised linear model