Table 4.

Numerical results of SPM comparisons of FDG uptake in CG vs. CSFAβ₄₂ + /amyR − , CSFAβ₄₂ + /amyR − vs. CSFAβ₄₂ + /amyR + , and CSFAβ₄₂ + /amyR + vs. A + T + 

Analysis	Cluster level					Voxel level
	Cluster p (FWE-corr)	Cluster p (FDR-corr)	Cluster extent	Cortical region	Z score of maximum	Talairach coordinates	Cortical region	BA
CG vs CSFAβ42 + /amyR −	0.000	0.000	31,175	L parietal lobe	Inf	− 36, − 74, 38	Precuneus	19
				L temporal lobe	Inf	− 52, − 56, − 10	Middle temporal gyrus	37
				L parietal lobe	7.63	− 48, − 48, 44	Inferior parietal lobule	40
	0.001	0.000	1795	L frontal lobe	3.81	− 26, 10, 58	Middle frontal gyrus	6
				L frontal lobe	3.61	− 30, 26, 46	Middle frontal gyrus	8
				L frontal Lobe	3.43	− 48, 30, 16	Inferior frontal gyrus	46
CSFAβ42 + /amyR − vs CSFAβ42 + /amyR +	0.000	0.000	6851	R frontal lobe	5.06	14, 62, 0	Medial frontal gyrus	10
				R frontal lobe	4.63	8, 60, 14	Medial frontal gyrus	10
				R limbic lobe	4.58	16, 32, 18	Anterior cingulate	32
CSFAβ42 + /amyR + vs A + T +	n.s			n.a	n.a	n.a	n.a	n.a

In the “cluster level” section (left), the number of voxels, corrected p-value of significance, and cortical region where the voxel is found are all reported for each significant cluster. In the “voxel level” section, all the coordinates of the correlation sites (with the Z-score of the maximum correlation point), the corresponding cortical region and BA are reported for each significant cluster (CG, control group; Inf., infinite; L, left; R, right; BA, Brodmann area). When the maximum correlation is achieved outside the gray matter, the nearest gray matter (within a range of 5 mm) is indicated by the corresponding BA