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. 2023 Jun 22;33(5):e13182. doi: 10.1111/bpa.13182

FIGURE 4.

FIGURE 4

Imaging and histopathological features of infant‐type hemispheric gliomas. (A–C) MR images of case #6, showing a large mass centered in the left temporal lobe, with dural contact. The mass has tissular and cystic parts on T2‐weighted images (B). The tissular part and cysts walls display avid contrast enhancement (A). CT scanner (C) shows tumoral bleeding (signs of an old hemorrhage). (D, E) MR images of case #19, showing a right temporo‐parietal mass with dural contact. The mass has mostly tissular content on T2‐weighted images, with central necrosis (E). The tumor display heterogeneous incomplete enhancement after gadolinium injection (D). (F, G) Densely cellular glial proliferation with necrosis and microvascular proliferation (case #15, HPS, magnification 100× and 400×). (H) Numerous mitoses (case #15, HPS, magnification 400×). (I, J) Presence of calcifications and siderophages (case #16, HPS, magnification 400×). (K) Elevated MIB1 labeling index (case #15, magnification 400×). Black scale bars represent 250 μm (F), and 50 μm (G–K). CT, computerized tomodensitometry; HPS, hematoxylin–phloxin–saffron; MR, magnetic resonance.