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. 2023 Jul 9;15(7):451. doi: 10.3390/toxins15070451

Figure A6.

Figure A6

Structure of digoxin (left), a cardiac glycoside that inhibits the function of the Na+/K+ ATPase (ATP1A; right) in the myocardium, which causes a decrease in heart rate [50]. A. lobata venom has similar differential expression effects to those of digoxin and other ATPase inhibitor drugs, based on connectivity analysis. Diagram from Reactome [51].