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Cell viability of HT-29 (A,C,E) and HCT-116 (B,D,F) spheroids treated for 24 and 48 h with the following: Mel HT-29 (A,B), CA (C,D) and CA-Mel (E,F). Data are represented as mean ± SD (n = 3). p values were calculated using ANOVA analysis with Tukey’s multiple comparison post-test. * p < 0.5, ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. C.
